Source:http://linkedlifedata.com/resource/pubmed/id/16129218
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2005-8-30
|
| pubmed:abstractText |
Sudden onset of nephrotic syndrome after allogeneic stem cell transplantation is rare and has been associated mostly with membranous glomerulonephritis related to chronic graft-versus-host disease (cGVHD). We report a case of nephrotic syndrome and rapidly progressive renal failure occurring in a young woman 3 years after allogeneic stem cell transplantation from her HLA-identical brother. In the renal biopsy, a diffuse mononuclear cell infiltrate was observed. Furthermore, histological analysis, immunofluorescence, and electron microscopy of the kidney specimen defined the diagnosis as minimal change disease, a T-cell-mediated glomerulopathy associated with lymphoproliferative disorders, but that has never been described as an isolated manifestation of cGVHD.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
1523-6838
|
| pubmed:author | |
| pubmed:issnType |
Electronic
|
| pubmed:volume |
46
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
550-6
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| pubmed:dateRevised |
2010-11-18
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| pubmed:meshHeading |
pubmed-meshheading:16129218-Acute Kidney Injury,
pubmed-meshheading:16129218-Adult,
pubmed-meshheading:16129218-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16129218-Chromosomes, Human, Y,
pubmed-meshheading:16129218-DNA,
pubmed-meshheading:16129218-Diagnosis, Differential,
pubmed-meshheading:16129218-Disease Progression,
pubmed-meshheading:16129218-Female,
pubmed-meshheading:16129218-Genetic Markers,
pubmed-meshheading:16129218-Graft vs Host Disease,
pubmed-meshheading:16129218-Humans,
pubmed-meshheading:16129218-Kidney,
pubmed-meshheading:16129218-Leukemic Infiltration,
pubmed-meshheading:16129218-Living Donors,
pubmed-meshheading:16129218-Male,
pubmed-meshheading:16129218-Nephrosis, Lipoid,
pubmed-meshheading:16129218-Nephrotic Syndrome,
pubmed-meshheading:16129218-Peripheral Blood Stem Cell Transplantation,
pubmed-meshheading:16129218-Polymerase Chain Reaction,
pubmed-meshheading:16129218-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:16129218-Transplantation, Homologous
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
Nephrotic syndrome and renal failure after allogeneic stem cell transplantation: novel molecular diagnostic tools for a challenging differential diagnosis.
|
| pubmed:affiliation |
Department of Clinical Pathophysiology, Center for Research, Transfer and High Education DE NOVO Therapies, University of Florence, Italy. p.romagnani@dfc.unifi.it
|
| pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|