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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0021289,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0041904,
umls-concept:C0086597,
umls-concept:C0185117,
umls-concept:C0202220,
umls-concept:C0225828,
umls-concept:C1457899,
umls-concept:C2911684
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pubmed:issue |
3
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pubmed:dateCreated |
2005-11-8
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pubmed:abstractText |
Myostatin, a negative regulator of muscle growth, is increased in hypertrophied and infarcted heart. However, the mechanism of regulation is not known. Mechanical stress is an important regulatory factor for cardiomyocyte growth. The aim of the study was to investigate the effect of cyclic stretch on the expression of myostatin gene in cardiomyocytes.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0008-6363
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
405-14
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16125157-Anastomosis, Surgical,
pubmed-meshheading:16125157-Animals,
pubmed-meshheading:16125157-Animals, Newborn,
pubmed-meshheading:16125157-Aorta,
pubmed-meshheading:16125157-Blotting, Northern,
pubmed-meshheading:16125157-Blotting, Western,
pubmed-meshheading:16125157-Cells, Cultured,
pubmed-meshheading:16125157-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:16125157-Enzyme Activation,
pubmed-meshheading:16125157-Gene Expression,
pubmed-meshheading:16125157-Insulin-Like Growth Factor I,
pubmed-meshheading:16125157-MAP Kinase Kinase 4,
pubmed-meshheading:16125157-Mitogen-Activated Protein Kinase 1,
pubmed-meshheading:16125157-Myocytes, Cardiac,
pubmed-meshheading:16125157-Myostatin,
pubmed-meshheading:16125157-Rats,
pubmed-meshheading:16125157-Rats, Wistar,
pubmed-meshheading:16125157-Stress, Mechanical,
pubmed-meshheading:16125157-Transforming Growth Factor beta,
pubmed-meshheading:16125157-Up-Regulation,
pubmed-meshheading:16125157-Venae Cavae,
pubmed-meshheading:16125157-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2005
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pubmed:articleTitle |
Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes.
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pubmed:affiliation |
Department of Education and Research, Shin Kong Wu Ho-Su Memorial Hospital, 95 Wen-Chang Road, Taipei 111, Taiwan. shyukg@ms12.hinet.net
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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