16123437

Source:http://linkedlifedata.com/resource/pubmed/id/16123437

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007603, umls-concept:C0007634, umls-concept:C0015127, umls-concept:C0035322, umls-concept:C0085403, umls-concept:C0086418, umls-concept:C0175677, umls-concept:C0205216, umls-concept:C1150182, umls-concept:C1314792
pubmed:issue	9
pubmed:dateCreated	2005-8-26
pubmed:abstractText	This study was undertaken to determine whether transient or sustained nonlethal oxidant injury can induce RPE cell membrane blebbing and alter RPE expression of matrix metalloproteinase (MMP)-2 and type IV collagen, two molecules that are necessary for regulation of the turnover of the RPE basal lamina.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/1R01 EY 014477, http://linkedlifedata.com/resource/pubmed/grant/1R01 EY 015249, http://linkedlifedata.com/resource/pubmed/grant/1R01 EY 13318
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7703701
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type IV, http://linkedlifedata.com/resource/pubmed/chemical/Green Fluorescent Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide, http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2, http://linkedlifedata.com/resource/pubmed/chemical/Oxidants, http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	0146-0404
pubmed:author	pubmed-author:CousinsScott WSW, pubmed-author:CsakyKarl GKG, pubmed-author:Marin-CastañoMaria EME
pubmed:issnType	Print
pubmed:volume	46
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	3331-40
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:16123437-Blotting, Western, pubmed-meshheading:16123437-Cell Count, pubmed-meshheading:16123437-Cell Membrane, pubmed-meshheading:16123437-Cell Survival, pubmed-meshheading:16123437-Cells, Cultured, pubmed-meshheading:16123437-Collagen Type IV, pubmed-meshheading:16123437-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:16123437-Exocytosis, pubmed-meshheading:16123437-Green Fluorescent Proteins, pubmed-meshheading:16123437-Humans, pubmed-meshheading:16123437-Hydrogen Peroxide, pubmed-meshheading:16123437-Matrix Metalloproteinase 2, pubmed-meshheading:16123437-Oxidants, pubmed-meshheading:16123437-Peroxidase, pubmed-meshheading:16123437-Pigment Epithelium of Eye, pubmed-meshheading:16123437-RNA, Messenger, pubmed-meshheading:16123437-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:16123437-Time Factors, pubmed-meshheading:16123437-Transfection, pubmed-meshheading:16123437-Up-Regulation
pubmed:year	2005
pubmed:articleTitle	Nonlethal oxidant injury to human retinal pigment epithelium cells causes cell membrane blebbing but decreased MMP-2 activity.
pubmed:affiliation	Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami School of Medicine, 1638 NW 10th Avenue, Miami, FL 33136, USA. mcastano@med.miami.edu
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural