Linked Life Data

16117133

Source:http://linkedlifedata.com/resource/pubmed/id/16117133

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-8-24
pubmed:abstractText
Toxicity test protocols for establishing the effect of zinc on the freshwater copepod Bryocamptus zschokkei are reported. In the absence of food, larval life-history stages were more sensitive than adult females to acute zinc exposure with a 96-h median lethal concentration of 0.62 mg Zn/L (0.52-0.73 mg Zn/L, 95% confidence intervals) for copepodids. The acute toxicity of zinc to adult females was also significantly reduced in the presence of food (a leaf disc). The main toxic effect of zinc in a life-cycle test was a reduction in the number of offspring per brood at 0.48 mg Zn/L. As this endpoint corresponded with zinc concentrations causing reduced juvenile survival, prolonged embryonic development times, and mortality during hatching, it appears that zinc had a direct toxic effect on the current brood rather than an indirect effect on egg production via maternal reallocation of resources. The lowest-observed-effect concentration for reproduction of measured zinc concentrations of 0.48 mg Zn/L corresponded with environmental concentrations of zinc causing reduced population densities of this copepod in the field. It is proposed that B. zschokkei is an ecologically relevant test species for evaluating the potential effects of contaminants on freshwater invertebrates and for giving insight into the mode of action of a test chemical.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0730-7268
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1528-31
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
A microplate freshwater copepod bioassay for evaluating acute and chronic effects of chemicals.
pubmed:affiliation
AstraZeneca Global Safety, Health and Environment, Brixham Environmental Laboratory, Freshwater Quarry, Brixham, Devon TQ5 8BA, United Kingdom. becky.brown@astrazeneca.com
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't