Linked Life Data

16115987

Source:http://linkedlifedata.com/resource/pubmed/id/16115987

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-8-23
pubmed:abstractText
Rarely, fire and patient injury result from the degradation of sevoflurane by desiccated Baralyme. The present investigation sought to determine whether high temperatures also arose with sevoflurane use in the presence of desiccated soda lime. We desiccated soda lime by directing a 10 L/min flow of oxygen through fresh absorbent. Using 1140 +/- 30 g (mean +/- sd) of this desiccated absorbent, we filled a single standard absorber canister placed in a standard anesthetic circuit to which we directed a 6 L/min flow of oxygen containing 1.5 minimum alveolar concentration (MAC) desflurane or sevoflurane, or 3.0 MAC desflurane, isoflurane, or sevoflurane (with and without concurrent delivery of 200 mL/min carbon dioxide). In an additional test, 2 canisters (rather than a single canister) containing desiccated absorbent were used and 3.0 MAC sevoflurane was applied. A 3-L reservoir bag served as a surrogate lung, and we ventilated this lung with a minute ventilation of 10 L/min. With desflurane at 1.5 MAC or 3.0 MAC or isoflurane at 3.0 MAC temperatures increased in 20 to 40 min to a peak of 30 degrees C to 45 degrees C and then declined. With 1.5 or 3.0 MAC sevoflurane, temperatures increased to approximately 90 degrees C, after which temperatures declined. Concurrent delivery of carbon dioxide and sevoflurane did not increase the peak temperatures reached. The use of 2 canisters increased the duration but not the peak of increased temperature reached with 3.0 MAC sevoflurane. No fires resulted from degradation of any anesthetic.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Inhalation, http://linkedlifedata.com/resource/pubmed/chemical/Baralyme, http://linkedlifedata.com/resource/pubmed/chemical/Barium Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Calcium Hydroxide, http://linkedlifedata.com/resource/pubmed/chemical/Carbon Dioxide, http://linkedlifedata.com/resource/pubmed/chemical/Isoflurane, http://linkedlifedata.com/resource/pubmed/chemical/Methyl Ethers, http://linkedlifedata.com/resource/pubmed/chemical/Oxides, http://linkedlifedata.com/resource/pubmed/chemical/Potassium Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Sodium Hydroxide, http://linkedlifedata.com/resource/pubmed/chemical/desflurane, http://linkedlifedata.com/resource/pubmed/chemical/sevoflurane, http://linkedlifedata.com/resource/pubmed/chemical/soda lime
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-2999
pubmed:author
pubmed:issnType
Print
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
753-7, table of contents
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Temperatures in soda lime during degradation of desflurane, isoflurane, and sevoflurane by desiccated soda lime.
pubmed:affiliation
Department of Anesthesia, S-455, University of California-San Francisco, CA 94143-0464, USA.
pubmed:publicationType
Journal Article, Comparative Study