| pubmed-article:16111740 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0015780 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0014939 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0004927 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0678335 | lld:lifeskim |
| pubmed-article:16111740 | lifeskim:mentions | umls-concept:C0443252 | lld:lifeskim |
| pubmed-article:16111740 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:16111740 | pubmed:dateCreated | 2005-10-10 | lld:pubmed |
| pubmed-article:16111740 | pubmed:abstractText | Estrogen effects on cocaine-induced reinstatement of lever responding were examined in sham-operated, vehicle-treated (SH+VEH), ovariectomized (OVX+VEH), and OVX female Wistar rats with estrogen replacement (OVX+EB). The effect of long- (64+/-1.56 days) and short-term (9 days) EB treatment on reinstatement of cocaine-seeking behavior was compared in Experiment 1 and 2, respectively, in order to compare the effect of EB when it was present during the development vs. expression of reinstatement of cocaine-seeking behavior. Rats were trained to self-administer 0.4 mg/kg/inf cocaine. After the acquisition criteria were met, rats continued to respond for cocaine for 2 h/day for a 14-day maintenance period. Cocaine was then replaced with saline and the 21-day extinction period commenced. Subsequently, rats were tested for reinstatement of lever responding on the previously drug-paired lever after alternating daily injections of saline or cocaine. In both experiments, there were no differences between groups in self-administration behavior during training, maintenance, or extinction. In Experiment 1, SH+VEH and chronically treated OVX+EB rats had greater cocaine-induced reinstatement than OVX+VEH rats. In Experiment 2, short-term treated OVX+EB rats also showed enhanced cocaine-induced reinstatement compared to OVX+VEH rats. The results indicate that EB-mediated enhancement of cocaine-induced reinstatement is dependent on EB presence during the expression of reinstatement but not during the formation of stimulus-reward associations during the development of cocaine-reinforced behavior. | lld:pubmed |
| pubmed-article:16111740 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16111740 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16111740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16111740 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16111740 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:16111740 | pubmed:issn | 0091-3057 | lld:pubmed |
| pubmed-article:16111740 | pubmed:author | pubmed-author:CarrollMarily... | lld:pubmed |
| pubmed-article:16111740 | pubmed:author | pubmed-author:RothMegan EME | lld:pubmed |
| pubmed-article:16111740 | pubmed:author | pubmed-author:LarsonErin... | lld:pubmed |
| pubmed-article:16111740 | pubmed:author | pubmed-author:AnkerJustin... | lld:pubmed |
| pubmed-article:16111740 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16111740 | pubmed:volume | 82 | lld:pubmed |
| pubmed-article:16111740 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16111740 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16111740 | pubmed:pagination | 98-108 | lld:pubmed |
| pubmed-article:16111740 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:meshHeading | pubmed-meshheading:16111740... | lld:pubmed |
| pubmed-article:16111740 | pubmed:year | 2005 | lld:pubmed |
| pubmed-article:16111740 | pubmed:articleTitle | Effect of short- vs. long-term estrogen on reinstatement of cocaine-seeking behavior in female rats. | lld:pubmed |
| pubmed-article:16111740 | pubmed:affiliation | Graduate Program in Neuroscience, University of Minnesota, MMC 392 Minneapolis, MN 55455, USA. larso323@umn.edu | lld:pubmed |
| pubmed-article:16111740 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16111740 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:16111740 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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