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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-8-8
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pubmed:abstractText |
Overexpression of cyclooxygenase-2 (COX-2) is implicated in many steps of cancer development. Single nucleotide polymorphisms (SNPs) in the COX-2 promoter might contribute to differential COX-2 expression and subsequent interindividual variability in susceptibility to cancer. This study sought to identify functional SNPs in the COX-2 promoter and evaluated their effects on the risk of developing esophageal squamous cell carcinoma (ESCC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:CoxK BKB,
pubmed-author:GuoYongliY,
pubmed-author:HongYuanY,
pubmed-author:KadlubarFred FFF,
pubmed-author:LinDongxinD,
pubmed-author:LiuZhihuaZ,
pubmed-author:MiaoXiaopingX,
pubmed-author:NingBaitangB,
pubmed-author:QiangBoqinB,
pubmed-author:ShenYanY,
pubmed-author:SongWenguangW,
pubmed-author:ZhangXinyuX,
pubmed-author:ZhangXuemeiX
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pubmed:issnType |
Print
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pubmed:volume |
129
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
565-76
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16083713-Adult,
pubmed-meshheading:16083713-Aged,
pubmed-meshheading:16083713-Base Sequence,
pubmed-meshheading:16083713-Case-Control Studies,
pubmed-meshheading:16083713-Confidence Intervals,
pubmed-meshheading:16083713-Cyclooxygenase 2,
pubmed-meshheading:16083713-Esophageal Neoplasms,
pubmed-meshheading:16083713-Esophagoscopy,
pubmed-meshheading:16083713-Female,
pubmed-meshheading:16083713-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16083713-Genetic Predisposition to Disease,
pubmed-meshheading:16083713-Genotype,
pubmed-meshheading:16083713-Haplotypes,
pubmed-meshheading:16083713-Humans,
pubmed-meshheading:16083713-Male,
pubmed-meshheading:16083713-Membrane Proteins,
pubmed-meshheading:16083713-Middle Aged,
pubmed-meshheading:16083713-Molecular Sequence Data,
pubmed-meshheading:16083713-Neoplasm Staging,
pubmed-meshheading:16083713-Odds Ratio,
pubmed-meshheading:16083713-Polymorphism, Genetic,
pubmed-meshheading:16083713-Prognosis,
pubmed-meshheading:16083713-Promoter Regions, Genetic,
pubmed-meshheading:16083713-Prostaglandin-Endoperoxide Synthases,
pubmed-meshheading:16083713-RNA, Messenger,
pubmed-meshheading:16083713-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16083713-Risk Assessment,
pubmed-meshheading:16083713-Sampling Studies
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pubmed:year |
2005
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pubmed:articleTitle |
Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer.
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pubmed:affiliation |
Department of Etiology and Carcinogenesis, Cancer Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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