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pubmed-article:16052171pubmed:abstractTextMyopia is the most common visual problem in the world. High myopia, the extreme form of myopia that can be complicated by retinal detachment and macular degeneration, affects 1%-2% of the general population. The genes responsible for nonsyndromic high myopia have not been identified although several chromosome loci have been suggested. Additional loci for the majority of high myopia, especially in Asian populations, await discovery. A large Chinese family with autosomal dominant high myopia was collected in order to map the genetic locus as an initial step towards identifying the genetic cause of high myopia in this family.lld:pubmed
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pubmed-article:16052171pubmed:articleTitleA new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612.lld:pubmed
pubmed-article:16052171pubmed:affiliationZhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China. qingjiongzhang@yahoo.comlld:pubmed
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