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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2005-7-29
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/OMIM/160700,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/310460,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/603221,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/605224,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/608367,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/608474,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/608908,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/609256,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/609257,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/609258,
http://linkedlifedata.com/resource/pubmed/xref/OMIM/609259
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pubmed:abstractText |
Myopia is the most common visual problem in the world. High myopia, the extreme form of myopia that can be complicated by retinal detachment and macular degeneration, affects 1%-2% of the general population. The genes responsible for nonsyndromic high myopia have not been identified although several chromosome loci have been suggested. Additional loci for the majority of high myopia, especially in Asian populations, await discovery. A large Chinese family with autosomal dominant high myopia was collected in order to map the genetic locus as an initial step towards identifying the genetic cause of high myopia in this family.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1090-0535
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
554-60
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16052171-Adult,
pubmed-meshheading:16052171-Asian Continental Ancestry Group,
pubmed-meshheading:16052171-Child,
pubmed-meshheading:16052171-Child, Preschool,
pubmed-meshheading:16052171-China,
pubmed-meshheading:16052171-Chromosome Mapping,
pubmed-meshheading:16052171-Chromosomes, Human, Pair 4,
pubmed-meshheading:16052171-DNA Mutational Analysis,
pubmed-meshheading:16052171-Electroretinography,
pubmed-meshheading:16052171-Female,
pubmed-meshheading:16052171-Genes, Dominant,
pubmed-meshheading:16052171-Genetic Linkage,
pubmed-meshheading:16052171-Genetic Markers,
pubmed-meshheading:16052171-Genetic Predisposition to Disease,
pubmed-meshheading:16052171-Genotype,
pubmed-meshheading:16052171-Humans,
pubmed-meshheading:16052171-Lod Score,
pubmed-meshheading:16052171-Male,
pubmed-meshheading:16052171-Middle Aged,
pubmed-meshheading:16052171-Myopia, Degenerative,
pubmed-meshheading:16052171-Pedigree,
pubmed-meshheading:16052171-Polymerase Chain Reaction
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pubmed:year |
2005
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pubmed:articleTitle |
A new locus for autosomal dominant high myopia maps to 4q22-q27 between D4S1578 and D4S1612.
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pubmed:affiliation |
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, People's Republic of China. qingjiongzhang@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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