Source:http://linkedlifedata.com/resource/pubmed/id/16029441
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-7-20
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pubmed:databankReference | |
pubmed:abstractText |
Here, we report on the identification and characterization of a novel human leukocyte antigen (HLA) DRB1 allele, DRB1*0830. This allele was identified in a candidate for hematopoietic stem cell donation. While the DNA sequence of HLA-DRB1*0830 most closely matches to DRB1*080202, its amino acid sequence resembles DRB1*080202 and DRB1*0813. Due to a substitution at nucleotide position 286 HLA-typing using sequence-specific oligonucleotide hybridization or amplification using sequence-specific primers gave inconclusive results. Allele-specific DNA sequencing confirmed a 286 T-->A substitution resulting in Phe67Ile.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0001-2815
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
160-2
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16029441-Alleles,
pubmed-meshheading:16029441-Base Sequence,
pubmed-meshheading:16029441-HLA-DR Antigens,
pubmed-meshheading:16029441-HLA-DRB1 Chains,
pubmed-meshheading:16029441-Histocompatibility Testing,
pubmed-meshheading:16029441-Humans,
pubmed-meshheading:16029441-Models, Molecular,
pubmed-meshheading:16029441-Molecular Sequence Data,
pubmed-meshheading:16029441-Nucleic Acid Hybridization,
pubmed-meshheading:16029441-Protein Structure, Tertiary
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pubmed:year |
2005
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pubmed:articleTitle |
Identification and characterization of a novel HLA-DRB1 allele, DRB1*0830*.
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pubmed:affiliation |
Institute of Transfusion Medicine, Campus Virchow-Klinikum, Charité-Universitätsmedizin Berlin, Berlin, Germany. berthold.hoppe@charite.de
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pubmed:publicationType |
Journal Article
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