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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2005-7-4
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pubmed:abstractText |
The intravenous anaesthetic propofol has been reported to exert neuroprotective actions by several mechanisms. This study has been designed to investigate the effects of propofol on intracellular calcium increase in cultured cerebrocortical neurons after exposure to pathological concentrations of N-methyl-D-aspartate (NMDA) mediated by potential direct interactions of propofol with NMDA receptors.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Intravenous,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Excitatory Amino Acid Agonists,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/N-Methylaspartate,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Chemicals,
http://linkedlifedata.com/resource/pubmed/chemical/Propofol,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, N-Methyl-D-Aspartate,
http://linkedlifedata.com/resource/pubmed/chemical/calcium green
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0265-0215
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
467-70
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:15991512-Anesthetics, Intravenous,
pubmed-meshheading:15991512-Animals,
pubmed-meshheading:15991512-Calcium,
pubmed-meshheading:15991512-Cells, Cultured,
pubmed-meshheading:15991512-Cerebral Cortex,
pubmed-meshheading:15991512-Cytosol,
pubmed-meshheading:15991512-Excitatory Amino Acid Agonists,
pubmed-meshheading:15991512-Female,
pubmed-meshheading:15991512-Fluorescent Dyes,
pubmed-meshheading:15991512-Microscopy, Confocal,
pubmed-meshheading:15991512-N-Methylaspartate,
pubmed-meshheading:15991512-Neurons,
pubmed-meshheading:15991512-Organic Chemicals,
pubmed-meshheading:15991512-Pregnancy,
pubmed-meshheading:15991512-Propofol,
pubmed-meshheading:15991512-Rats,
pubmed-meshheading:15991512-Rats, Sprague-Dawley,
pubmed-meshheading:15991512-Receptors, N-Methyl-D-Aspartate
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pubmed:year |
2005
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pubmed:articleTitle |
Effects of propofol on N-methyl-D-aspartate receptor-mediated calcium increase in cultured rat cerebrocortical neurons.
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pubmed:affiliation |
Eberhard-Karls-University, Department of Anaesthesiology and Intensive Care, Tuebingen, Germany. christian.grasshoff@uni-tuebingen.de
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pubmed:publicationType |
Journal Article
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