Linked Life Data

1599059

Source:http://linkedlifedata.com/resource/pubmed/id/1599059

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1992-7-7
pubmed:abstractText
Propofol and midazolam were compared for intra-operative patient-controlled sedation in 40 ASA 1 day patients undergoing surgical extraction of third molar teeth under local anaesthesia. All patients initially received 0.7 micrograms.kg-1 fentanyl. Patients in the propofol group self-administered 20 mg (2 ml over 6 s) bolus doses of propofol; successful demands averaged 8.0 (SD 4.4) and unsuccessful demands (during the 1 min lockout period) 2.8 (SD 4.1). The midazolam group self-administered 0.5 mg (2 ml over 6 s) bolus doses and averaged 14.0 (SD 6.3) and 17.6 (SD 19.8) successful and unsuccessful demands respectively. Postoperative memory, measured with delayed free recall, and postoperative mental performance, measured with the frequency accrual speed test index, were both significantly less impaired in the propofol group. Although there was no significant difference in patient satisfaction, measured postoperatively, propofol was judged the more suitable agent for patient-controlled sedation, because of its more rapid response to fluctuating intra-operative requirements, superior recovery characteristics and beneficial effect on mood.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0003-2409
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
376-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Intra-operative patient-controlled sedation. Comparison of patient-controlled propofol with patient-controlled midazolam.
pubmed:affiliation
Department of Anaesthesia and Intensive Care, Royal Adelaide Hospital, North Terrace, South Australia.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't