|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:dateCreated |
2005-6-30
|
|
pubmed:abstractText |
Gamma-aminobutyric acid (GABA)-A/benzodiazepine receptors (BZRs) play an important inhibitory role in epileptogenesis. [123I]Iomazenil (123I-IMZ) is a specific ligand for central-type (or neuronal-type) BNRs and is available for single-photon emission computed tomography (SPECT) in brain disorders. We demonstrated alterations of central-type BZRs in human focal epilepsies and their experimental models.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0013-9580
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
46 Suppl 5
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
184-8
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:15987275-Adult,
pubmed-meshheading:15987275-Amygdala,
pubmed-meshheading:15987275-Animals,
pubmed-meshheading:15987275-Autoradiography,
pubmed-meshheading:15987275-Cerebral Cortex,
pubmed-meshheading:15987275-Dentate Gyrus,
pubmed-meshheading:15987275-Disease Models, Animal,
pubmed-meshheading:15987275-Epilepsies, Partial,
pubmed-meshheading:15987275-Epilepsy, Temporal Lobe,
pubmed-meshheading:15987275-Female,
pubmed-meshheading:15987275-Flumazenil,
pubmed-meshheading:15987275-Hippocampus,
pubmed-meshheading:15987275-Humans,
pubmed-meshheading:15987275-Iodine Radioisotopes,
pubmed-meshheading:15987275-Kainic Acid,
pubmed-meshheading:15987275-Kindling, Neurologic,
pubmed-meshheading:15987275-Magnetic Resonance Imaging,
pubmed-meshheading:15987275-Male,
pubmed-meshheading:15987275-Neocortex,
pubmed-meshheading:15987275-Rats,
pubmed-meshheading:15987275-Receptors, GABA-A,
pubmed-meshheading:15987275-Regional Blood Flow,
pubmed-meshheading:15987275-Tomography, Emission-Computed, Single-Photon
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Central-type benzodiazepine receptors and epileptogenesis: basic mechanisms and clinical validity.
|
|
pubmed:affiliation |
Department of Neuropsychiatry, Faculty of Medicine, Kagawa Medical University, Kagawa, Japan. neuropsy@kms.ac.jp
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
