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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2005-8-12
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pubmed:abstractText |
Recent observations suggest the involvement of the gastrointestinal tract in the pathogenesis of islet autoimmunity. Thus, the modulation of gut-associated lymphoid tissue may represent a means to affect the natural history of the disease. Oral administration of probiotic bacteria can modulate local and systemic immune responses; consequently, we investigated the effects of oral administration of the probiotic compound VSL#3 on the occurrence of diabetes in non-obese diabetic (NOD) mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0012-186X
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pubmed:author |
pubmed-author:BoirivantMM,
pubmed-author:BonatoVV,
pubmed-author:CalcinaroFF,
pubmed-author:CandeloroPP,
pubmed-author:CornellR ARA,
pubmed-author:De SimoneCC,
pubmed-author:Di MarioUU,
pubmed-author:DionisiSS,
pubmed-author:DottaFF,
pubmed-author:FalorniAA,
pubmed-author:FerrettiEE,
pubmed-author:GrassiLL,
pubmed-author:GulinoAA,
pubmed-author:MarinaroMM,
pubmed-author:MarzottiSS
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1565-75
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:15986236-Adoptive Transfer,
pubmed-meshheading:15986236-Animals,
pubmed-meshheading:15986236-Blood Glucose,
pubmed-meshheading:15986236-Cell Separation,
pubmed-meshheading:15986236-Cyclophosphamide,
pubmed-meshheading:15986236-Diabetes Mellitus, Type 1,
pubmed-meshheading:15986236-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15986236-Female,
pubmed-meshheading:15986236-Immunoenzyme Techniques,
pubmed-meshheading:15986236-Immunohistochemistry,
pubmed-meshheading:15986236-Insulin,
pubmed-meshheading:15986236-Interleukin-10,
pubmed-meshheading:15986236-Islets of Langerhans,
pubmed-meshheading:15986236-Mice,
pubmed-meshheading:15986236-Mice, Inbred NOD,
pubmed-meshheading:15986236-Pancreas,
pubmed-meshheading:15986236-Probiotics,
pubmed-meshheading:15986236-Protein Synthesis Inhibitors,
pubmed-meshheading:15986236-Spleen
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pubmed:year |
2005
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pubmed:articleTitle |
Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse.
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pubmed:affiliation |
Department of Internal Medicine, University of Perugia, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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