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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2005-6-28
pubmed:abstractText
Gastric biopsy materials of 4074 consecutive Japanese patients undergoing esophagogastroduodenoscopy were reviewed, along with those of 15 patients with Helicobacter heilmannii infection (11, chronic gastritis; four, mucosa-associated lymphoid tissue (MALT) lymphoma). In four patients with H. heilmannii infection, the materials were examined by transmission electronmicroscopy. Urea breath test (three patients) and antibody test (five patients) were performed in patients with H. heilmannii infection. In two patients with MALT lymphoma, H. heilmannii was eradicated. The prevalence of H. heilmannii was 0.1% in the consecutive series. In chronic gastritis, the gastric mucosa was endoscopically normal (13.3%), had erythema (33.3%), or had erosions (53.3%); histologically, it showed no epithelial change, mild mononuclear cell infiltration, and slight and focal neutrophil infiltration; Helicobacter heilmannii was positive with anti-H. pylori antibody, and was detected in the mucous gel layer and in foveolae. In MALT lymphoma, the gastric mucosa was coarsely granular with enlarged mucosal folds without ulcers (two cases), with small ulcers (one case), or with multiple erosions (one case). Urea breath test and antibody test were both negative. Eradication of H. heilmannii resulted in remission of MALT lymphoma. Helicobacter heilmannii infection is therefore uncommon in Japanese adults, but is associated with chronic gastritis and gastric MALT lymphoma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1320-5463
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
398-404
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:15982214-2-Pyridinylmethylsulfinylbenzimidazoles, pubmed-meshheading:15982214-Adult, pubmed-meshheading:15982214-Aged, pubmed-meshheading:15982214-Amoxicillin, pubmed-meshheading:15982214-Anti-Infective Agents, pubmed-meshheading:15982214-Clarithromycin, pubmed-meshheading:15982214-Endoscopy, Gastrointestinal, pubmed-meshheading:15982214-Female, pubmed-meshheading:15982214-Gastritis, pubmed-meshheading:15982214-Helicobacter Infections, pubmed-meshheading:15982214-Helicobacter heilmannii, pubmed-meshheading:15982214-Humans, pubmed-meshheading:15982214-Japan, pubmed-meshheading:15982214-Lymphoma, B-Cell, Marginal Zone, pubmed-meshheading:15982214-Male, pubmed-meshheading:15982214-Microscopy, Electron, Transmission, pubmed-meshheading:15982214-Middle Aged, pubmed-meshheading:15982214-Omeprazole, pubmed-meshheading:15982214-Stomach, pubmed-meshheading:15982214-Treatment Outcome
pubmed:year
2005
pubmed:articleTitle
Helicobacter heilmannii infection: clinical, endoscopic and histopathological features in Japanese patients.
pubmed:affiliation
Second Department of Internal Medicine, Shinshu University School of Medicine, Shinshu University, Nagano, Japan.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't