Linked Life Data

15979165

Source:http://linkedlifedata.com/resource/pubmed/id/15979165

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2005-7-25
pubmed:abstractText
Botulinum neurotoxins are the most potent toxins designed by nature. They are produced by Clostridium bacteria to cause long-lasting paralysis and death. However, in the past century one member of the botulinum family--botulinum neurotoxin type A--has been put to good use, and is now widely employed in clinical neurology and, even more often, in beauty clinics. This article will critically assess the value of individual members of the botulinum family for experimental neuroscience and medicine. The seven botulinum neurotoxins all act by targeting the same vesicle fusion machinery, and yet they cause paralysis of different durations. The distinct behaviors of botulinum neurotoxins will be discussed, with the aim of highlighting advantages and limitations for their future exploitation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0166-2236
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
446-52
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Beyond BOTOX: advantages and limitations of individual botulinum neurotoxins.
pubmed:affiliation
Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. email@bazbek.com
pubmed:publicationType
Journal Article, Review, Historical Article