pubmed-article:15955029 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:15955029 | lifeskim:mentions | umls-concept:C0025914 | lld:lifeskim |
pubmed-article:15955029 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
pubmed-article:15955029 | lifeskim:mentions | umls-concept:C0005839 | lld:lifeskim |
pubmed-article:15955029 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:15955029 | pubmed:dateCreated | 2005-6-15 | lld:pubmed |
pubmed-article:15955029 | pubmed:abstractText | 1. The pressor action of noradrenaline and its blockade by selective alpha(1)-adrenoceptor antagonists in the pithed mouse were evaluated. 2. Chloroethylclonidine (alpha(1B/D)-adrenoceptor alkylating agent) or BMY 7378 (alpha(1D)-adrenoceptor antagonist), both at 1 mg kg(-1), did not block the increase in blood pressure induced by noradrenaline. 3. 5-Methylurapidil (alpha(1A)-adrenoceptor antagonist), at 0.1 mg kg(-1), displaced the dose-response curve approximately six-fold to the right. 4. The results support the idea that the pithed mouse vasculature express alpha(1A)-adrenoceptors and suggest that it is a good model to study the roles of alpha(1)-adrenoceptors in gene knockout or overexpression. | lld:pubmed |
pubmed-article:15955029 | pubmed:language | eng | lld:pubmed |
pubmed-article:15955029 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:15955029 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:15955029 | pubmed:month | Jul | lld:pubmed |
pubmed-article:15955029 | pubmed:issn | 1474-8665 | lld:pubmed |
pubmed-article:15955029 | pubmed:author | pubmed-author:Villalobos-Mo... | lld:pubmed |
pubmed-article:15955029 | pubmed:author | pubmed-author:IbarraMM | lld:pubmed |
pubmed-article:15955029 | pubmed:author | pubmed-author:López-Guerrer... | lld:pubmed |
pubmed-article:15955029 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:15955029 | pubmed:volume | 25 | lld:pubmed |
pubmed-article:15955029 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:15955029 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:15955029 | pubmed:pagination | 101-3 | lld:pubmed |
pubmed-article:15955029 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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pubmed-article:15955029 | pubmed:year | 2005 | lld:pubmed |
pubmed-article:15955029 | pubmed:articleTitle | Postjunctional alpha1-adrenoceptors in the vasculature of the pithed mouse are of the alpha1A-subtype. | lld:pubmed |
pubmed-article:15955029 | pubmed:affiliation | Departamento de Farmacobiología, Centro de Investigación y de Estudios Avanzados, Sede Sur, México D.F. | lld:pubmed |
pubmed-article:15955029 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:15955029 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:15955029 | lld:pubmed |