Source:http://linkedlifedata.com/resource/pubmed/id/15953653
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2005-7-19
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pubmed:abstractText |
The tryptophan operon of Bacillus subtilis serves as an excellent model for investigating transcription regulation in Gram-positive bacteria. In this article, we extend this knowledge by analyzing the predicted regulatory regions in the trp operons of other fully sequenced Gram-positive bacteria. Interestingly, it appears that in eight of the organisms examined, transcription of the trp operon appears to be regulated by tandem T-box elements. These regulatory elements have recently been described in the trp operons of two bacterial species. Single T-box elements are commonly found in Gram-positive bacteria in operons encoding aminoacyl tRNA synthetases and proteins performing other functions. Different regulatory mechanisms appear to be associated with variations of trp gene organization within the trp operon.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0168-9525
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
432-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15953653-Bacillus,
pubmed-meshheading:15953653-Bacillus subtilis,
pubmed-meshheading:15953653-Base Sequence,
pubmed-meshheading:15953653-Genes, Bacterial,
pubmed-meshheading:15953653-Gram-Positive Bacteria,
pubmed-meshheading:15953653-Models, Genetic,
pubmed-meshheading:15953653-Operon,
pubmed-meshheading:15953653-RNA, Bacterial,
pubmed-meshheading:15953653-Sequence Homology, Nucleic Acid,
pubmed-meshheading:15953653-Tryptophan
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pubmed:year |
2005
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pubmed:articleTitle |
New insights into regulation of the tryptophan biosynthetic operon in Gram-positive bacteria.
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pubmed:affiliation |
Department of Molecular Microbiology, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Cuernavaca, Morelos 62271, Mexico.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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