Source:http://linkedlifedata.com/resource/pubmed/id/15915006
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2005-5-25
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pubmed:abstractText |
The development of HFA-based pMDIs has proved difficult due to differences in the physico-chemical properties of CFC and HFA propellants. However, the development of solution formulations instead of suspensions has provided a way to formulate products whose cloud characteristics can be modulated in a controlled manner by permitting different formulation and device hardware variables. The new approach has proved successful in formulating several different drugs including steroids and has now been applied to developing a formoterol Modulite solution formulation characterized by good chemical stability, delivery performance, and clinical results.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0025-7931
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
72 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3-5
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:15915006-Aerosol Propellants,
pubmed-meshheading:15915006-Bronchodilator Agents,
pubmed-meshheading:15915006-Chemistry, Pharmaceutical,
pubmed-meshheading:15915006-Drug Stability,
pubmed-meshheading:15915006-Ethanolamines,
pubmed-meshheading:15915006-Humans,
pubmed-meshheading:15915006-Metered Dose Inhalers,
pubmed-meshheading:15915006-Technology, Pharmaceutical
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pubmed:year |
2005
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pubmed:articleTitle |
Modulite: a simple solution to a difficult problem.
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pubmed:affiliation |
Vectura Ltd., Chippenham, UK. david.lewis@vectura.com
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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