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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2005-5-18
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pubmed:abstractText |
Although cancer cells appear to maintain the machinery for intrinsic apoptosis, defects in the pathway develop during malignant transformation, preventing apoptosis from occurring. How to specifically induce apoptosis in cancer cells remains unclear.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ACSL5 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/AIFM1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/APAF1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Apaf1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Apoptosis Inducing Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Apoptotic Protease-Activating...,
http://linkedlifedata.com/resource/pubmed/chemical/Cardiolipins,
http://linkedlifedata.com/resource/pubmed/chemical/Caspases,
http://linkedlifedata.com/resource/pubmed/chemical/Coenzyme A Ligases,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes c,
http://linkedlifedata.com/resource/pubmed/chemical/Enzyme Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Flavoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Pdcd8 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Triazenes,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Suppressor Protein p53,
http://linkedlifedata.com/resource/pubmed/chemical/triacsin C
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1460-2105
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pubmed:author |
pubmed-author:HamadaJun-ichiJ,
pubmed-author:IshikawaYuichiY,
pubmed-author:KatoYoY,
pubmed-author:MashimaTetsuoT,
pubmed-author:MochizukiMikikoM,
pubmed-author:MoriuchiTetsuyaT,
pubmed-author:Oh-haraTomokoT,
pubmed-author:SatoShigeoS,
pubmed-author:SugimotoYoshikazuY,
pubmed-author:TadaMitsuhiroM,
pubmed-author:TomodaHiroshiH,
pubmed-author:TsuruoTakashiT,
pubmed-author:YamazakiKanamiK,
pubmed-author:YamoriTakaoT
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pubmed:issnType |
Electronic
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pubmed:day |
18
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
765-77
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pubmed:dateRevised |
2007-7-25
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pubmed:meshHeading |
pubmed-meshheading:15900046-Animals,
pubmed-meshheading:15900046-Antineoplastic Agents,
pubmed-meshheading:15900046-Apoptosis,
pubmed-meshheading:15900046-Apoptosis Inducing Factor,
pubmed-meshheading:15900046-Apoptotic Protease-Activating Factor 1,
pubmed-meshheading:15900046-Blotting, Western,
pubmed-meshheading:15900046-Brain Neoplasms,
pubmed-meshheading:15900046-Breast Neoplasms,
pubmed-meshheading:15900046-Cardiolipins,
pubmed-meshheading:15900046-Caspases,
pubmed-meshheading:15900046-Coenzyme A Ligases,
pubmed-meshheading:15900046-Colonic Neoplasms,
pubmed-meshheading:15900046-Cytochromes c,
pubmed-meshheading:15900046-Enzyme Activation,
pubmed-meshheading:15900046-Enzyme Inhibitors,
pubmed-meshheading:15900046-Female,
pubmed-meshheading:15900046-Flavoproteins,
pubmed-meshheading:15900046-Gene Transfer Techniques,
pubmed-meshheading:15900046-Humans,
pubmed-meshheading:15900046-Lung Neoplasms,
pubmed-meshheading:15900046-Membrane Proteins,
pubmed-meshheading:15900046-Mice,
pubmed-meshheading:15900046-Mice, Nude,
pubmed-meshheading:15900046-Mitochondria,
pubmed-meshheading:15900046-Neoplasms, Experimental,
pubmed-meshheading:15900046-Proteins,
pubmed-meshheading:15900046-RNA, Small Interfering,
pubmed-meshheading:15900046-Sequence Analysis, DNA,
pubmed-meshheading:15900046-Stomach Neoplasms,
pubmed-meshheading:15900046-Transfection,
pubmed-meshheading:15900046-Transplantation, Heterologous,
pubmed-meshheading:15900046-Triazenes,
pubmed-meshheading:15900046-Tumor Suppressor Protein p53
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pubmed:year |
2005
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pubmed:articleTitle |
p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.
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pubmed:affiliation |
Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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