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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-8-1
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pubmed:abstractText |
It is well known that cyclophosphamide (Cy) treatment before sensitization paradoxically enhances rather than suppresses contact hypersensitivity (CH) reactions. In fact, Cy-treated mice developed a significant (p < 0.05) increase of the CH reactions to 2,4,6-trinitro-1-chrolobenzene (TNCB) in comparison with untreated mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0923-1811
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15899580-Animals,
pubmed-meshheading:15899580-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15899580-Cell Proliferation,
pubmed-meshheading:15899580-Cyclophosphamide,
pubmed-meshheading:15899580-Dermatitis, Contact,
pubmed-meshheading:15899580-Female,
pubmed-meshheading:15899580-Flow Cytometry,
pubmed-meshheading:15899580-Immunosuppressive Agents,
pubmed-meshheading:15899580-Mice,
pubmed-meshheading:15899580-Mice, Inbred BALB C,
pubmed-meshheading:15899580-Picryl Chloride,
pubmed-meshheading:15899580-Receptors, Interleukin-2,
pubmed-meshheading:15899580-T-Lymphocytes,
pubmed-meshheading:15899580-Time Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity.
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pubmed:affiliation |
Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Kanazawa-ku, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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