Linked Life Data

15862934

Source:http://linkedlifedata.com/resource/pubmed/id/15862934

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2005-5-2
pubmed:abstractText
Abdominal bloating is a relevant, troublesome, and poorly understood clinical problem. Despite its clinical importance, bloating remains substantially ignored, without proper clinical classification, known pathophysiology, and effective treatment. It is not even clear to what extent the complaints of individual patients correlate with objective evidence of abdominal distension, and this uncertainly regarding the subjective or objective origin of the complaints further adds to confusion. This article proposed a framework for investigating bloating, considering key factors potentially involved in its pathophysiology: distorted sensation, physical abdominal expansion, and abdominal wall dystony. Some data indicate that patients complaining of bloating have impaired transit and tolerance of intestinal gas loads. The problem does not seem to be too much gas,however, but rather abnormal responses to gas. Furthermore, abnormal control of abdominal muscle activity in these patients may contribute to objective distension. Bloating, like many other abdominal symptoms,probably represents a heterogeneous condition produced by a combination of pathophysiological mechanisms that differ among individual patients,resulting in a polymorphic clinical presentation.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0889-8553
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
257-69
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The pathogenesis of bloating and visible distension in irritable bowel syndrome.
pubmed:affiliation
University Hospital Vall d'Hebron, Autonomous University of Barcelona, PG Vall d'Hebron S/N, Barcelona 08035, Spain. fernando.azpiroz@wol.es
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural