Source:http://linkedlifedata.com/resource/pubmed/id/15862755
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2005-5-2
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pubmed:abstractText |
The prevalence of co-morbidity among elderly lymphoma patients is associated with a decrease in the use of chemotherapy. This study assessed the independent prognostic effect of co-morbidity in 1551 unselected lymphoma patients, diagnosed between 1995 and 2001 in the area of the population-based Eindhoven Cancer Registry. The prevalence of serious co-morbidity was 58% for patients with Hodgkin's disease (HD) who were over 60 years of age and 66% for patients with non-Hodgkin's lymphoma (NHL) who were over 60 years of age. The administration of chemotherapy declined in the presence of co-morbidity for elderly patients with early-stage HD and elderly patients with aggressive NHL. Co-morbidity was associated with a 10-20% decline in 5-year survival. Whether less frequent application of chemotherapy in the presence of co-morbidity is justified as far as complications, prognosis and quality of life are concerned requires further investigation.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0959-8049
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1051-7
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pubmed:meshHeading |
pubmed-meshheading:15862755-Adult,
pubmed-meshheading:15862755-Age Distribution,
pubmed-meshheading:15862755-Aged,
pubmed-meshheading:15862755-Aged, 80 and over,
pubmed-meshheading:15862755-Comorbidity,
pubmed-meshheading:15862755-Female,
pubmed-meshheading:15862755-Follow-Up Studies,
pubmed-meshheading:15862755-Hodgkin Disease,
pubmed-meshheading:15862755-Humans,
pubmed-meshheading:15862755-Lymphoma, Non-Hodgkin,
pubmed-meshheading:15862755-Male,
pubmed-meshheading:15862755-Middle Aged,
pubmed-meshheading:15862755-Netherlands,
pubmed-meshheading:15862755-Prevalence,
pubmed-meshheading:15862755-Prognosis,
pubmed-meshheading:15862755-Proportional Hazards Models,
pubmed-meshheading:15862755-Registries,
pubmed-meshheading:15862755-Survival Analysis,
pubmed-meshheading:15862755-Survival Rate
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pubmed:year |
2005
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pubmed:articleTitle |
Independent prognostic effect of co-morbidity in lymphoma patients: results of the population-based Eindhoven Cancer Registry.
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pubmed:affiliation |
Department of Medical Oncology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
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pubmed:publicationType |
Journal Article
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