Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-6-18
|
| pubmed:abstractText |
A newly developed Western blot assay for antibody to hepatitis E virus (anti-HEV) was used to evaluate 39 cases of acute pediatric hepatitis and 39 control patients in Khartoum, Sudan. The mean age of cases was 6.5 years (range, 2-14); 64% were male. Acute hepatitis A (IgM anti-HAV-positive) was diagnosed in 13 cases, acute hepatitis B (IgM anti-HBc-positive) in 1, and acute hepatitis E (positive for IgM anti-HEV) in 23 (59%). None of the cases with IgM anti-HAV or IgM anti-HBc had IgM anti-HEV; 3 controls had IgM anti-HEV. Acute hepatitis E was associated with recent contact with a family member or acquaintance with jaundice and the presence of indoor plumbing. The newly developed hepatitis E assay appeared to be specific for the diagnosis of acute icteric non-A, non-B hepatitis. Hepatitis E was found to be the most common cause of acute sporadic hepatitis in children living in an urban area of Africa.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
165
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1001-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1583317-Acute Disease,
pubmed-meshheading:1583317-Adolescent,
pubmed-meshheading:1583317-Age Factors,
pubmed-meshheading:1583317-Blotting, Western,
pubmed-meshheading:1583317-Case-Control Studies,
pubmed-meshheading:1583317-Child,
pubmed-meshheading:1583317-Child, Preschool,
pubmed-meshheading:1583317-Female,
pubmed-meshheading:1583317-Hepatitis A,
pubmed-meshheading:1583317-Hepatitis Antibodies,
pubmed-meshheading:1583317-Hepatitis B,
pubmed-meshheading:1583317-Hepatitis E,
pubmed-meshheading:1583317-Hepatitis E virus,
pubmed-meshheading:1583317-Humans,
pubmed-meshheading:1583317-Immunoglobulin G,
pubmed-meshheading:1583317-Immunoglobulin M,
pubmed-meshheading:1583317-Infant,
pubmed-meshheading:1583317-Liver Function Tests,
pubmed-meshheading:1583317-Male,
pubmed-meshheading:1583317-Sudan,
pubmed-meshheading:1583317-Urban Population
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Acute sporadic hepatitis E in Sudanese children: analysis based on a new western blot assay.
|
| pubmed:affiliation |
Infectious Disease Department, US Naval Medical Research Institute, Bethesda, Maryland.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
|