Source:http://linkedlifedata.com/resource/pubmed/id/15830301
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2005-4-14
|
| pubmed:abstractText |
Postoperative surveillance is an important part of the curative therapy of colorectal cancer patients. The effort and effectiveness of these surveillance programs are controversially discussed. We analyzed the practiced follow-up of patients who had undergone a curative resection of colorectal cancer to demonstrate the difficulty to validate the performed surveillance program and to point out possible improvements. For a follow-up period of 37 months (median) we included 530 patients with at least one postoperative examination. 70 patients ended the follow-up prematurely - out of these 56 % quit the surveillance during the first 18 months. Another 68 patients died during the follow-up period. Cancer recurred in 28 % of the patients (n = 109 metastasis, n = 26 local recurrences, 18 patients developed a secondary cancer). 90 % of these recurrences occurred within the first three years. 3525 follow-up examinations took place within 79 months. Patient histories and physical examinations were not helpful for the diagnosis of local recurrences; neither were laboratory routine screenings meaningful. Carcinoembryonic antigen (CEA) and CA 19 - 9 tests, ultrasonographic studies, chest XD-rays and colonoscopic procedures had a higher diagnostic value on the other hand. We demonstrated the problematic nature of the evaluation of different follow-up tests concerning their validity as they were part of a complex postoperative surveillance program. It is also important to point out that the success of the postoperative surveillance depends strongly on the compliance of the patients. To increase this compliance we suggest that the follow-up of patients should be more strongly oriented towards the incidence of recurrences.
|
| pubmed:language |
ger
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0044-2771
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
43
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
357-65
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| pubmed:dateRevised |
2009-11-11
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| pubmed:meshHeading |
pubmed-meshheading:15830301-Aftercare,
pubmed-meshheading:15830301-CA-19-9 Antigen,
pubmed-meshheading:15830301-Carcinoembryonic Antigen,
pubmed-meshheading:15830301-Colonoscopy,
pubmed-meshheading:15830301-Colorectal Neoplasms,
pubmed-meshheading:15830301-Diagnostic Imaging,
pubmed-meshheading:15830301-Female,
pubmed-meshheading:15830301-Follow-Up Studies,
pubmed-meshheading:15830301-Humans,
pubmed-meshheading:15830301-Lung Neoplasms,
pubmed-meshheading:15830301-Male,
pubmed-meshheading:15830301-Neoplasm Recurrence, Local,
pubmed-meshheading:15830301-Neoplasm Staging,
pubmed-meshheading:15830301-Neoplasms, Second Primary,
pubmed-meshheading:15830301-Patient Compliance,
pubmed-meshheading:15830301-Patient Dropouts,
pubmed-meshheading:15830301-Predictive Value of Tests,
pubmed-meshheading:15830301-Survival Rate
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
[Patient compliance and efficacy of diagnostic procedures in the surveillance of colorectal cancer: experience from a cancer center].
|
| pubmed:affiliation |
Abteilung für Allgemein-, Visceral- und Unfallchirurgie der Chirurgischen Klinik, Universitätsklinikum Heidelberg. Stefan_Riedl@med.uni-heidelberg.de
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|