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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2005-4-8
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pubmed:abstractText |
[reaction: see text] Additions of chiral allenylzinc and indium reagents to N-Boc alaninal were examined as a possible route to a C20-C26 segment of superstolide A. Allenylzinc reagents, prepared in situ by palladiozincation of (R)- and (S)-5-pivalyloxy-3-butyn-2-ol mesylate, showed excellent reagent control to afford the anti,syn and anti,anti diastereomers as the nearly exclusive adducts.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1523-7060
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1593-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15816760-Alanine,
pubmed-meshheading:15816760-Animals,
pubmed-meshheading:15816760-Catalysis,
pubmed-meshheading:15816760-Cyclization,
pubmed-meshheading:15816760-Indicators and Reagents,
pubmed-meshheading:15816760-Macrolides,
pubmed-meshheading:15816760-Molecular Structure,
pubmed-meshheading:15816760-Porifera,
pubmed-meshheading:15816760-Pyrans,
pubmed-meshheading:15816760-Stereoisomerism,
pubmed-meshheading:15816760-Tetrahydronaphthalenes
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pubmed:year |
2005
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pubmed:articleTitle |
Synthesis of a C20-C26 segment of superstolide A by addition of a chiral allenylzinc reagent to (R)-N-boc alaninal.
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pubmed:affiliation |
Department of Chemistry, P.O. Box 400319, University of Virginia, Charlottesville, Virginia 22904, USA. jam5x@virginia.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
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