Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2005-4-8
pubmed:abstractText
The interference in the metabolism of a drug by another drug, food or other foreign chemical is commonly observed and often leads to clinically significant adverse drug reactions. In Jamaica, there is an extensive use of natural products as medicines, although there is little information on whether natural medicines are used along with prescription medicines, which might increase the likelihood of drug adversities. This current pilot survey was initiated to gain information on the prevalence of such polypharmacy practices. Two concurrent surveys were carried out in Kingston (an urban parish) and Clarendon (a rural parish) in 743 patients above age 14 years with diabetes mellitus, hypertension and gastrointestinal disorders of persons who visited health centres and pharmacies. Patrons visiting these places at various times of the day were informed of the nature of the questionnaire and willing participants with the above disease conditions and who were on prescription medicines were included in the survey. The results indicated that 80% of the respondents reported combining natural products in their treatment along with prescription medicines, with only 13% of those patients informing their physicians of such practices. Such polypharmacy practices were independent of the type of disease among both males and females and was statistically most prevalent (p < 0.001) in the 47-57-year age group. There was a significant association (p < 0.001) between such treatment practices and place of residence with 92% of the rural community engaging in polypharmacy but 70% of the urban did likewise. Therefore, being aware of the prevalence of multiple therapy practices would be especially useful when designing a pharmaco-vigilance system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0043-3144
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
400-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:15816268-Adolescent, pubmed-meshheading:15816268-Adult, pubmed-meshheading:15816268-Age Factors, pubmed-meshheading:15816268-Community Health Centers, pubmed-meshheading:15816268-Diabetes Mellitus, pubmed-meshheading:15816268-Drug Prescriptions, pubmed-meshheading:15816268-Female, pubmed-meshheading:15816268-Gastrointestinal Diseases, pubmed-meshheading:15816268-Health Care Surveys, pubmed-meshheading:15816268-Herb-Drug Interactions, pubmed-meshheading:15816268-Humans, pubmed-meshheading:15816268-Hypertension, pubmed-meshheading:15816268-Male, pubmed-meshheading:15816268-Middle Aged, pubmed-meshheading:15816268-Pharmacies, pubmed-meshheading:15816268-Pharmacy Service, Hospital, pubmed-meshheading:15816268-Phytotherapy, pubmed-meshheading:15816268-Pilot Projects, pubmed-meshheading:15816268-Polypharmacy, pubmed-meshheading:15816268-Questionnaires, pubmed-meshheading:15816268-Self Medication
pubmed:year
2004
pubmed:articleTitle
The practice of polypharmacy involving herbal and prescription medicines in the treatment of diabetes mellitus, hypertension and gastrointestinal disorders in Jamaica.
pubmed:affiliation
Natural Products Institute and Tropical Medicine Research Institute, The University of the West Indies, Kingston 7, Jamaica. thejani.delgoda@uwimona.edu.jm
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't