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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2005-4-5
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pubmed:abstractText |
Because of a severe shortage of human donor pancreases, pig islets are considered to be an attractive donor source. Our previous in vitro study revealed that adult pig islets have strong non-Galalpha1-3Galbeta1-4GlcNAc-R (alpha-Gal) antigenicity, including the Hanganutziu-Deicher (H-D) antigen, especially in N-linked sugars. In this study, the issue of whether islets from N-acetylglucosaminyltransferase-III (GnT-III) transgenic pigs can prolong their survival in cynomolgus monkeys was examined.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0908-665X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15807771-Animals,
pubmed-meshheading:15807771-Animals, Genetically Modified,
pubmed-meshheading:15807771-Antibodies, Heterophile,
pubmed-meshheading:15807771-Antigens, Heterophile,
pubmed-meshheading:15807771-Diabetes Mellitus, Experimental,
pubmed-meshheading:15807771-Graft Survival,
pubmed-meshheading:15807771-Humans,
pubmed-meshheading:15807771-Islets of Langerhans,
pubmed-meshheading:15807771-Islets of Langerhans Transplantation,
pubmed-meshheading:15807771-Kidney,
pubmed-meshheading:15807771-Macaca fascicularis,
pubmed-meshheading:15807771-N-Acetylglucosaminyltransferases,
pubmed-meshheading:15807771-Swine,
pubmed-meshheading:15807771-Transplantation, Heterologous
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pubmed:year |
2005
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pubmed:articleTitle |
Survival of adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) in cynomolgus monkeys.
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pubmed:affiliation |
Division of Organ Transplantation, Department of Regenerative Medicine, Osaka University Graduate School of Medicine, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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