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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-6-9
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pubmed:abstractText |
While polymorphonuclear leukocytes may contribute to the "no-reflow" phenomenon after focal cardiac and skeletal muscle ischemia/reperfusion, their contribution to acute focal cerebral ischemia is unresolved. We have examined the role of polymorphonuclear leukocytes in microvascular perfusion defects after focal cerebral ischemia/reperfusion in a baboon model of reversible middle cerebral artery occlusion with the anti-CD18 monoclonal antibody IB4, which inhibits neutrophil adherence to endothelium.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0039-2499
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
712-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:1579969-Animals,
pubmed-meshheading:1579969-Antibodies, Monoclonal,
pubmed-meshheading:1579969-Brain Ischemia,
pubmed-meshheading:1579969-Cell Adhesion,
pubmed-meshheading:1579969-Cerebrovascular Circulation,
pubmed-meshheading:1579969-Microcirculation,
pubmed-meshheading:1579969-Nervous System,
pubmed-meshheading:1579969-Neutrophils,
pubmed-meshheading:1579969-Papio,
pubmed-meshheading:1579969-Reperfusion,
pubmed-meshheading:1579969-Vascular Patency
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pubmed:year |
1992
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pubmed:articleTitle |
Inhibition of polymorphonuclear leukocyte adherence suppresses no-reflow after focal cerebral ischemia in baboons.
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pubmed:affiliation |
Department of Molecular and Experimental Medicine, Scripps Research Institute, La Jolla, Calif. 92037.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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