Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2005-3-29
pubmed:abstractText
The incidence of laryngeal cancer is strongly connected with exposure to tobacco smoke containing at least 40 genotoxic carcinogens. DNA lesions induced by tobacco smoke carcinogens can be turned into stable mutations. Oncogenes and tumor suppressor genes are first of all responsible for initiation of carcinogenesis. The same time cells provide such self-protection processes as: carcinogen detoxication, DNA repair and apoptosis. The initiation of carcinogenesis followed by oncogenesis results from the competition between DNA lesions/mutations formation and the protection processes; the latter are genetically controlled.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0033-2240
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1197-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
[Molecular and cellular changes following exposure to tobacco smoke causing laryngeal cancer. An outline of the problem].
pubmed:affiliation
Institut Genetyki Cz?owieka Polskiej Akademii Nauk w Poznaniu. szyfkris@man.poznan.pl
pubmed:publicationType
Journal Article, English Abstract, Review