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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0015259,
umls-concept:C0018270,
umls-concept:C0018787,
umls-concept:C0030705,
umls-concept:C0127400,
umls-concept:C0162638,
umls-concept:C0264793,
umls-concept:C0301630,
umls-concept:C0332281,
umls-concept:C1363844,
umls-concept:C1516240,
umls-concept:C1555029,
umls-concept:C1749467
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|
pubmed:issue |
2
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|
pubmed:dateCreated |
2005-3-23
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|
pubmed:abstractText |
Recent experimental and clinical data indicate that abnormal inflammatory and apoptotic processes contribute to the progression of chronic heart failure (CHF). We sought to study the effects of growth hormone (GH) on circulating soluble apoptosis mediators, and to investigate whether these GH-induced anti-apoptotic effects are associated with the reduction of left ventricular (LV) volumes and attenuation of exercise intolerance in idiopathic dilated cardiomyopathy (IDC) patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1741-8267
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
164-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15785303-Apoptosis,
pubmed-meshheading:15785303-Cardiomyopathy, Dilated,
pubmed-meshheading:15785303-Cross-Over Studies,
pubmed-meshheading:15785303-Cytokines,
pubmed-meshheading:15785303-Dose-Response Relationship, Drug,
pubmed-meshheading:15785303-Drug Administration Schedule,
pubmed-meshheading:15785303-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:15785303-Exercise Tolerance,
pubmed-meshheading:15785303-Fas Ligand Protein,
pubmed-meshheading:15785303-Female,
pubmed-meshheading:15785303-Follow-Up Studies,
pubmed-meshheading:15785303-Growth Hormone,
pubmed-meshheading:15785303-Heart Function Tests,
pubmed-meshheading:15785303-Humans,
pubmed-meshheading:15785303-Injections, Subcutaneous,
pubmed-meshheading:15785303-Male,
pubmed-meshheading:15785303-Membrane Glycoproteins,
pubmed-meshheading:15785303-Probability,
pubmed-meshheading:15785303-Reference Values,
pubmed-meshheading:15785303-Risk Assessment,
pubmed-meshheading:15785303-Treatment Outcome,
pubmed-meshheading:15785303-Tumor Necrosis Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy.
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pubmed:affiliation |
Second Department of Cardiovascular Medicine, Onassis Cardiac Surgery Centre Athens, Greece. jparissis@yahoo.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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