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rdf:type |
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lifeskim:mentions |
umls-concept:C0023907,
umls-concept:C0034693,
umls-concept:C0060623,
umls-concept:C0101389,
umls-concept:C0193398,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C0521425,
umls-concept:C1527178,
umls-concept:C1705938,
umls-concept:C2587213
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pubmed:issue |
61
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pubmed:dateCreated |
2005-3-23
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pubmed:abstractText |
Activin A is an autocrine inhibitor of cell growth in the liver. The biological activity of activin A is mediated by a heteromeric receptor complex. Follistatin (FS) binds to activin and inhibits its biological effects, and acts as a negative regulator of muscle cells. The role of activin receptors during liver regeneration following a hepatectomy has not been fully assessed. This study investigates the mechanism underlying how activin receptors regulate hepatocyte growth, and the effects of intravenous administration of FS during liver regeneration.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Activin Receptors, Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Follistatin,
http://linkedlifedata.com/resource/pubmed/chemical/Inhbb protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Inhibin-beta Subunits,
http://linkedlifedata.com/resource/pubmed/chemical/Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/activin receptor type II-A,
http://linkedlifedata.com/resource/pubmed/chemical/follistatin, 288-amino acid isoform,
http://linkedlifedata.com/resource/pubmed/chemical/inhibin beta A subunit
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-6390
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
60-6
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:15782995-Activin Receptors, Type II,
pubmed-meshheading:15782995-Animals,
pubmed-meshheading:15782995-Follistatin,
pubmed-meshheading:15782995-Hepatectomy,
pubmed-meshheading:15782995-Hepatocytes,
pubmed-meshheading:15782995-Inhibin-beta Subunits,
pubmed-meshheading:15782995-Injections, Intravenous,
pubmed-meshheading:15782995-Liver Regeneration,
pubmed-meshheading:15782995-Male,
pubmed-meshheading:15782995-Proteins,
pubmed-meshheading:15782995-Rats
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pubmed:articleTitle |
Possible endocrine control by follistatin 315 during liver regeneration based on changes in the activin receptor after a partial hepatectomy in rats.
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pubmed:affiliation |
Department of Digestive Surgery, University of Tokushima Tokushima, Japan. c-ktakamura@eph.pref.ehime.jp
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pubmed:publicationType |
Journal Article
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