Linked Life Data

15781316

Source:http://linkedlifedata.com/resource/pubmed/id/15781316

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2005-3-22
pubmed:abstractText
Stromelysin-3 (ST3) overexpression is associated with poor patient clinical outcome in numerous carcinomas. The ST3 is expressed by peritumoral fibroblast-like cells. Review of the literature shows that ST3 is an active partner of cancer cells along the whole natural cancer history, and is essential for optimal tumor development as it reduces death of cancer cells invading adjacent connective tissues at the primary tumor site. Paradoxically, ST3 lowers metastasis development in vivo in mice. However, this beneficial effect does not counterbalance the deleterious anti-apoptotic function of ST3.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9084
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-306
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
From a unique cell to metastasis is a long way to go: clues to stromelysin-3 participation.
pubmed:affiliation
Institut de génétique et de biologie moléculaire et cellulaire (IGBMC), CNRS/Inserm U184/ULP BP 163, 67404 Illkirch cedex, CU de Strasbourg, France. rio@igbmc.u-strasbg.fr
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't