Linked Life Data

15780420

Source:http://linkedlifedata.com/resource/pubmed/id/15780420

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2005-3-22
pubmed:abstractText
Type 1 (reversal or upgrading) reactions occur during or after chemotherapy in around 10% leprosy patients [Int J Lepr Other Mycobact Dis 61 (1993) 8-15]. The cause of this immunological upgrading is incompletely defined, although the approximately 2-fold increased risk of reaction in patients vaccinated with Mycobacterium w suggests that infection by mycobacteria other than Mycobacterium leprae may trigger this phenomenon [Vaccine 13 (1995) 1102-1110]. We report a case of borderline lepromatous leprosy in which we studied the antigenic specificity of peripheral blood mononuclear cells immediately before, and then during, a Type 1 reaction which provides more direct evidence in favor of this hypothesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0163-4453
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
242-3
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Antigenic trigger for type 1 reaction in leprosy.
pubmed:affiliation
Division of Medicine, Wellcome Trust Centre for Research Clinical Tropical Medicine, Imperial College London, 2nd Floor Wright Fleming Institute, Norfolk Place, London W2 1PG, UK. r.j.wilkinson@imperial.ac.uk
pubmed:publicationType
Journal Article, Case Reports