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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2005-3-14
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pubmed:abstractText |
The role of antibody dependent cellular cytotoxicity (ADCC) in HCV infection is unclear at present. Antibodies mediating ADCC are usually directed against viral envelope proteins. As cell surface expression of the HCV envelope E2 protein has been shown, the HCV E2 protein is an especially promising candidate target for ADCC.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0168-8278
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pubmed:author |
pubmed-author:BrackmannHans HHH,
pubmed-author:HoughtonMichaelM,
pubmed-author:InchauspéGenevièveG,
pubmed-author:LanghansBettinaB,
pubmed-author:LeifeldLudgerL,
pubmed-author:MatzBertfriedB,
pubmed-author:NattermannJacobJ,
pubmed-author:SauerbruchTilmanT,
pubmed-author:SchneidersAngelika MariaAM,
pubmed-author:SchulzMonikaM,
pubmed-author:SpenglerUlrichU
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
499-504
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15763336-Adolescent,
pubmed-meshheading:15763336-Adult,
pubmed-meshheading:15763336-Aged,
pubmed-meshheading:15763336-Animals,
pubmed-meshheading:15763336-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:15763336-CHO Cells,
pubmed-meshheading:15763336-Cricetinae,
pubmed-meshheading:15763336-Female,
pubmed-meshheading:15763336-Hepacivirus,
pubmed-meshheading:15763336-Hepatitis C, Chronic,
pubmed-meshheading:15763336-Hepatitis C Antibodies,
pubmed-meshheading:15763336-Humans,
pubmed-meshheading:15763336-Male,
pubmed-meshheading:15763336-Middle Aged,
pubmed-meshheading:15763336-Recombinant Proteins,
pubmed-meshheading:15763336-Viral Envelope Proteins,
pubmed-meshheading:15763336-Viral Load
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pubmed:year |
2005
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pubmed:articleTitle |
Serum antibodies against the hepatitis C virus E2 protein mediate antibody-dependent cellular cytotoxicity (ADCC).
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pubmed:affiliation |
Department of General Internal Medicine I, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany. jacob.nattermann@ukb.uni-bonn.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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