Linked Life Data

15757804

Source:http://linkedlifedata.com/resource/pubmed/id/15757804

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2005-3-10
pubmed:abstractText
Recently, new pathomorphologic information about early-stage small hepatocellular carcinoma (HCC) and the multi-step process of human hepatocarcinogenesis has been obtained, along with advances in the development of diagnostic modalities. The most valuable information is that in the majority of cases HCC arises as a very well differentiated cancer and proliferates with a stepwise process of dedifferentiation. In addition, it has been suggested that many HCCs seem to arise from dysplastic nodules (DNs) on the basis of the following evidence: the presence of DNs containing HCC foci, frequent association of DNs in the vicinity of HCC, and clinical progression from DN to HCC. However, as many HCCs are still detected at an advanced stage, it is also important to understand not only the classical pathologic features of HCC but also unusual features such as scirrhous change, sarcomatous change, fibrolamellar variant, and intra-bile duct or intra-atrial tumor growth.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1521-6918
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-62
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Histopathology of liver cancers.
pubmed:affiliation
Department of Pathology, School of Medicine, Kurume University, 67 Asahi-machi, Kurume-shi 830-0011, Fukuoka, Japan. kojiro@med.kurume-u.ac.jp
pubmed:publicationType
Journal Article, Review