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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1992-6-4
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pubmed:abstractText |
The effects of initial clinical variables on short-term prognosis are analyzed in a cross-sectional study of 574 multiple sclerosis patients from 7 centers in 5 European countries. Patients with a primary progressive course had a 2.3 higher mean disability score (EDSS) than the primary remittent group after a mean duration of disease of 6.6 years. High age at onset was associated with a primary progressive course, and was also related to increased risk of a rapid shift to a secondary progressive course. Among the remittent patients without a secondary progressive course a high age at onset was significantly correlated to a higher disability score. In the whole remittent group the presence of pyramidal and cerebellar symptoms at onset predicted both a high disability score and a rapid shift to a secondary progression, while the effect was reverse for sensory and visual symptoms. No difference between the sexes was found.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0001-6314
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
212-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1575007-Adult,
pubmed-meshheading:1575007-Age Factors,
pubmed-meshheading:1575007-Disability Evaluation,
pubmed-meshheading:1575007-Europe,
pubmed-meshheading:1575007-Female,
pubmed-meshheading:1575007-Humans,
pubmed-meshheading:1575007-Male,
pubmed-meshheading:1575007-Multiple Sclerosis,
pubmed-meshheading:1575007-Neurologic Examination,
pubmed-meshheading:1575007-Prognosis,
pubmed-meshheading:1575007-Sex Factors
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pubmed:year |
1992
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pubmed:articleTitle |
Early prognostic factors for disability in multiple sclerosis, a European multicenter study.
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pubmed:affiliation |
Department of Neurology, University of Bergen, Norway.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|