Linked Life Data

15741346

Source:http://linkedlifedata.com/resource/pubmed/id/15741346

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-3-17
pubmed:databankReference
pubmed:abstractText
The structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein, was determined by NMR spectroscopy. The structure is dominated by a beta-barrel sandwich. A two-stranded anti-parallel beta-sheet, which seals off one end of the beta-barrel, is flanked by two flexible loops rich in acidic amino acids. Although this fold often provides a ligand binding site, the structure did not reveal an appreciable cavity inside the beta-barrel. The three-dimensional structure of At3g04780.1-des15 provides an entry point for understanding its functional role and those of its mammalian homologs.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-10212987, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-10826702, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-11103992, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-11470603, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-11884135, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-11985582, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-12051947, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-12091873, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-12565051, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-2002850, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-8744573, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-8805557, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-9008363, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-9367762, http://linkedlifedata.com/resource/pubmed/commentcorrection/15741346-9668102
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0961-8368
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1059-63
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Solution structure of At3g04780.1-des15, an Arabidopsis thaliana ortholog of the C-terminal domain of human thioredoxin-like protein.
pubmed:affiliation
Center for Eukaryotic Structural Genomics, Department of Biochemistry, 433 Babcock Drive, University of Wisconsin-Madison, Madison, WI 53706-1544, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural