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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-2-22
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pubmed:abstractText |
Septic shock leads to derangement of cellular metabolism. Enhanced heat shock protein 70 (HSP-70) can preserve cellular metabolism after other forms of cellular stress. Glutamine (GLN) can enhance lung HSP-70 expression after lethal endotoxemia. However, it is unknown whether GLN can enhance HSP-70 expression and attenuate lung metabolic dysfunction after sublethal endotoxemia. Our aim was to determine whether GLN could upregulate HSP-70 and attenuate metabolic dysfunction in lung tissue after sublethal endotoxemia.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0899-9007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
214-23
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15723751-Animals,
pubmed-meshheading:15723751-Blotting, Western,
pubmed-meshheading:15723751-Fluorescent Antibody Technique,
pubmed-meshheading:15723751-Gene Expression Regulation,
pubmed-meshheading:15723751-Glutamine,
pubmed-meshheading:15723751-HSP70 Heat-Shock Proteins,
pubmed-meshheading:15723751-Lipopolysaccharides,
pubmed-meshheading:15723751-Lung,
pubmed-meshheading:15723751-Magnetic Resonance Spectroscopy,
pubmed-meshheading:15723751-Male,
pubmed-meshheading:15723751-Quercetin,
pubmed-meshheading:15723751-Random Allocation,
pubmed-meshheading:15723751-Rats,
pubmed-meshheading:15723751-Rats, Sprague-Dawley
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pubmed:year |
2005
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pubmed:articleTitle |
Glutamine attenuates endotoxin-induced lung metabolic dysfunction: potential role of enhanced heat shock protein 70.
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pubmed:affiliation |
Department of Anesthesiology, University of Colorado Health Sciences Center, Denver, Colorado, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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