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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2005-2-15
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pubmed:abstractText |
Barrett's oesophagus is defined as the replacement of squamous oesophageal epithelium by intestinal metaplasia in the distal oesophagus. It is a fairly frequent complication of gastro-oesophageal reflux disease (GORD): 5-10% of patients with GORD suffer from Barrett's oesophagus. GORD is essential for the development of Barrett's oesophagus.1 Intestinal metaplasia is a premalignant lesion that may further develop into dysplasia and lead to adenocarcinoma of the oesophagus. The latter now accounts for almost 50% of oesophageal cancer cases in western countries, and the largest increase in its incidence was recorded during the past two decades. Patients with Barrett's oesophagus have a 2-25% risk of developing mild to severe dysplasia and a 2-5% risk of having adenocarcinoma: 30-150 times higher than the risk in the general population. Forty to fifty per cent of Barrett's oesophagus patients with severe dysplasia would present adenocarcinoma within 5 years.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/15711006-10080844,
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0017-5749
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
54 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
i33-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:15711006-Adenocarcinoma,
pubmed-meshheading:15711006-Barrett Esophagus,
pubmed-meshheading:15711006-Esophageal Neoplasms,
pubmed-meshheading:15711006-Esophagoscopy,
pubmed-meshheading:15711006-Esophagus,
pubmed-meshheading:15711006-Humans,
pubmed-meshheading:15711006-Metaplasia,
pubmed-meshheading:15711006-Mucous Membrane,
pubmed-meshheading:15711006-Photochemotherapy,
pubmed-meshheading:15711006-Postoperative Complications,
pubmed-meshheading:15711006-Precancerous Conditions
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pubmed:year |
2005
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pubmed:articleTitle |
Barrett's oesophagus: the new endoscopic modalities have a future.
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pubmed:affiliation |
Department of Gastroenterology and Hepatopancreatology, ULB - Hôpital Erasme, Route de Lennik 808, B - 1070 Brussels, Belgium. jdeviere@ulb.ac.be
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pubmed:publicationType |
Journal Article,
Review
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