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rdf:type |
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lifeskim:mentions |
|
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pubmed:issue |
3
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pubmed:dateCreated |
2005-2-15
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|
pubmed:abstractText |
In patients with severe acute liver dysfunction, i.v. phylloquinone (vitamin K1) may be given to exclude vitamin K deficiency, rather than impaired hepatic synthesis of coagulation factors alone, as the cause of the coagulopathy. However, there have been no studies of the pharmacokinetics or efficacy of i.v. or oral K1 in such patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0168-8278
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
365-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15710219-Acute Disease,
pubmed-meshheading:15710219-Administration, Oral,
pubmed-meshheading:15710219-Adolescent,
pubmed-meshheading:15710219-Adult,
pubmed-meshheading:15710219-Aged,
pubmed-meshheading:15710219-Double-Blind Method,
pubmed-meshheading:15710219-Female,
pubmed-meshheading:15710219-Half-Life,
pubmed-meshheading:15710219-Humans,
pubmed-meshheading:15710219-Injections, Intravenous,
pubmed-meshheading:15710219-Intestinal Absorption,
pubmed-meshheading:15710219-Liver Diseases,
pubmed-meshheading:15710219-Male,
pubmed-meshheading:15710219-Middle Aged,
pubmed-meshheading:15710219-Placebos,
pubmed-meshheading:15710219-Vitamin K 1
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pubmed:year |
2005
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pubmed:articleTitle |
Pharmacokinetics and efficacy of oral versus intravenous mixed-micellar phylloquinone (vitamin K1) in severe acute liver disease.
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pubmed:affiliation |
Institute of Liver Studies, King's College Hospital, London, UK. stephen.pereira@ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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