Source:http://linkedlifedata.com/resource/pubmed/id/15698562
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2005-2-8
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pubmed:abstractText |
We describe the design of a database and software for managing and organizing protein crystallization data. We also outline the considerations behind the design of a fast web interface linking protein production data, crystallization images, and automated image analysis. The database and associated interfaces underpin the Oxford Protein Production Facility (OPPF) crystallization laboratory, collecting, in a routine and automatic manner, up to 100,000 images per day. Over 17 million separate images are currently held in this database. We discuss the substantial scientific benefits automated tracking, imaging, and analysis of crystallizations offers to the structural biologist: analysis of the time course of the trial and easy analysis of trials with related crystallization conditions. Features of this system address requirements common to many crystallographic laboratories that are currently setting up (semi-)automated crystallization imaging systems.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0969-2126
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pubmed:author |
pubmed-author:BerryIan MIM,
pubmed-author:DiproseJonathan MJM,
pubmed-author:EsnoufRobert MRM,
pubmed-author:HarlosKarlK,
pubmed-author:JonesE YvonneEY,
pubmed-author:MayoChristopher JCJ,
pubmed-author:OwensRay JRJ,
pubmed-author:StuartDavid IDI,
pubmed-author:WalterThomas STS,
pubmed-author:WilsonJulieJ
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-82
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
2005
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pubmed:articleTitle |
Benefits of automated crystallization plate tracking, imaging, and analysis.
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pubmed:affiliation |
The Division of Structural Biology, The Henry Wellcome Building for Genomic Medicine, Roosevelt Drive, Oxford, OX3 7BN, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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