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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2005-2-1
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pubmed:abstractText |
Liver regeneration is a unique response directed to restore liver mass after resection or injury. The survival and proliferative signals triggered during this process are conveyed by a complex network of cytokines and growth factors acting in an orderly manner. Activation of the epidermal growth factor receptor is thought to play an important role in liver regeneration. Amphiregulin is a member of the epidermal growth factor family whose expression is not detectable in healthy liver. We have investigated the expression of amphiregulin in liver injury and its role during liver regeneration after partial hepatectomy.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
128
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
424-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:15685553-Adult,
pubmed-meshheading:15685553-Aged,
pubmed-meshheading:15685553-Animals,
pubmed-meshheading:15685553-Biopsy,
pubmed-meshheading:15685553-DNA Replication,
pubmed-meshheading:15685553-Disease Models, Animal,
pubmed-meshheading:15685553-Female,
pubmed-meshheading:15685553-Gene Expression Regulation,
pubmed-meshheading:15685553-Glycoproteins,
pubmed-meshheading:15685553-Hepatocytes,
pubmed-meshheading:15685553-Humans,
pubmed-meshheading:15685553-Intercellular Signaling Peptides and Proteins,
pubmed-meshheading:15685553-Liver,
pubmed-meshheading:15685553-Liver Regeneration,
pubmed-meshheading:15685553-Male,
pubmed-meshheading:15685553-Mice,
pubmed-meshheading:15685553-Middle Aged,
pubmed-meshheading:15685553-Rats,
pubmed-meshheading:15685553-Rats, Wistar
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pubmed:year |
2005
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pubmed:articleTitle |
Amphiregulin: an early trigger of liver regeneration in mice.
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pubmed:affiliation |
Division of Hepatology and Gene Therapy, Cntro de Investigción Médica Aplicada, Facultad e Medicina,Universidad de Navarra, Pamplona, Spain.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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