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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-26
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pubmed:abstractText |
Tumor cells undergo a variety of biological changes under sustained hypoxic conditions, allowing cells to survive and retain their clonogenic potential. The purpose of this study is to relate the expression of the hypoxia marker carbonic anhydrase 9 (CA9) to the uptake of iododeoxyuridine (IdUrd), a marker of proliferation, in head and neck squamous cell carcinomas. Colocalization of IdUrd and CA9 may identify an important subpopulation of tumor cells that might be responsible for repopulation and disease progression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1078-0432
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
97-106
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pubmed:meshHeading |
pubmed-meshheading:15671533-Adult,
pubmed-meshheading:15671533-Aged,
pubmed-meshheading:15671533-Aged, 80 and over,
pubmed-meshheading:15671533-Anoxia,
pubmed-meshheading:15671533-Antigens, Neoplasm,
pubmed-meshheading:15671533-Biopsy,
pubmed-meshheading:15671533-Carbonic Anhydrases,
pubmed-meshheading:15671533-Carcinoma,
pubmed-meshheading:15671533-Cell Proliferation,
pubmed-meshheading:15671533-Disease Progression,
pubmed-meshheading:15671533-Disease-Free Survival,
pubmed-meshheading:15671533-Head and Neck Neoplasms,
pubmed-meshheading:15671533-Humans,
pubmed-meshheading:15671533-Hydrogen-Ion Concentration,
pubmed-meshheading:15671533-Idoxuridine,
pubmed-meshheading:15671533-Image Processing, Computer-Assisted,
pubmed-meshheading:15671533-Immunohistochemistry,
pubmed-meshheading:15671533-Middle Aged,
pubmed-meshheading:15671533-Neoplasm Metastasis,
pubmed-meshheading:15671533-Nucleic Acid Synthesis Inhibitors,
pubmed-meshheading:15671533-Prognosis,
pubmed-meshheading:15671533-Time Factors
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pubmed:year |
2005
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pubmed:articleTitle |
Colocalization of carbonic anhydrase 9 expression and cell proliferation in human head and neck squamous cell carcinoma.
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pubmed:affiliation |
Department of Radiation Oncology, University Medical Center, St. Radboud, Nijmegen, The Netherlands. i.hoogsteen@rther.umcn.nl
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pubmed:publicationType |
Journal Article
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