The critical events in the clinical course of prostate cancer are the occurrence of metastasis and the induction of the hormone-refractory status of the disease. In order to investigate the factors responsible for these events, we need appropriate in vivo models.
Department of Urology, Graduate School of Medical Science, 13-1, Kanazawa University, Kanazawa-city, Ishikawa 920-8641, Japan. tak1019@kenroku.kanazawa-u.ac.jp