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pubmed-article:15663566pubmed:abstractTextChronic rejection is a major problem for all lung transplant programmes, which is functionally manifested by fixed airflow limitation, Bronchiolitis Obliterans Syndrome (BOS). The inclusion of a Pre-BOS category, BOS(0 approximately p), in newly revised guidelines, recognizes the potential importance of early changes. We have previously demonstrated reticular basement membrane (Rbm) thickening in clinically stable lung transplant recipients free from BOS. The present study extends this, testing the hypothesis that inhaled corticosteroid (ICS) therapy will lead to a decrease in Rbm thickness in lung transplant recipients.lld:pubmed
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pubmed-article:15663566pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:15663566pubmed:articleTitleReticular basement membrane thickening in airways of lung transplant recipients is not affected by inhaled corticosteroids.lld:pubmed
pubmed-article:15663566pubmed:affiliationApplied Immunobiology and Transplantation Group, Freeman Hospital and University of Newcastle-upon-Tyne, Newcastle-upon-Tyne NE7 7DN, UK. Chris.Ward@newcastle.ac.uklld:pubmed
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