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rdf:type |
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lifeskim:mentions |
umls-concept:C0021390,
umls-concept:C0040649,
umls-concept:C0040661,
umls-concept:C0205548,
umls-concept:C0449774,
umls-concept:C0805732,
umls-concept:C1335960,
umls-concept:C1366753,
umls-concept:C1521761,
umls-concept:C1548425,
umls-concept:C1710082,
umls-concept:C1879547
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-18
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pubmed:abstractText |
Cytokine signaling pathways involving transcription factors of the signal transducers and activators of transcription (STAT) family play a key role in the pathogenesis of inflammatory bowel diseases (IBD). STAT proteins are latent cytoplasmic transcription factors that induce transcription upon phosphorylation, dimerization, and nuclear translocation. However, their activation pattern in IBD is poorly understood. The aim of our study was to characterize STAT-expression in IBD.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/STAT1 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/STAT2 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT3 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/STAT4 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/STAT6 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Trans-Activators
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0002-9270
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
64-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15654782-CD4-Positive T-Lymphocytes,
pubmed-meshheading:15654782-Case-Control Studies,
pubmed-meshheading:15654782-Colon,
pubmed-meshheading:15654782-DNA-Binding Proteins,
pubmed-meshheading:15654782-Humans,
pubmed-meshheading:15654782-Inflammatory Bowel Diseases,
pubmed-meshheading:15654782-STAT1 Transcription Factor,
pubmed-meshheading:15654782-STAT2 Transcription Factor,
pubmed-meshheading:15654782-STAT3 Transcription Factor,
pubmed-meshheading:15654782-STAT4 Transcription Factor,
pubmed-meshheading:15654782-STAT6 Transcription Factor,
pubmed-meshheading:15654782-Trans-Activators
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pubmed:year |
2005
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pubmed:articleTitle |
Activation pattern of signal transducers and activators of transcription (STAT) factors in inflammatory bowel diseases.
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pubmed:affiliation |
Department of 1st Medical Clinic, Department of Pathology, Johannes-Gutenberg-University of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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