|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001674,
umls-concept:C0017968,
umls-concept:C0019682,
umls-concept:C0019699,
umls-concept:C0033684,
umls-concept:C0205266,
umls-concept:C0205314,
umls-concept:C0678594,
umls-concept:C0679622,
umls-concept:C1367553,
umls-concept:C2348438
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|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2005-1-14
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|
pubmed:abstractText |
To evaluate the delivery of a novel HIV-1 antigen (gp120dV2 SF162) by surface adsorption or encapsulation within polylactide-co-glycolide microparticles and to compare both the formulations for their ability to preserve functional activity as measured by binding to soluble CD4.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0724-8741
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
21
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
2148-52
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|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15648244-Adsorption,
pubmed-meshheading:15648244-Animals,
pubmed-meshheading:15648244-Antigens, CD4,
pubmed-meshheading:15648244-CHO Cells,
pubmed-meshheading:15648244-Cricetinae,
pubmed-meshheading:15648244-Drug Compounding,
pubmed-meshheading:15648244-HIV Envelope Protein gp120,
pubmed-meshheading:15648244-HIV-1,
pubmed-meshheading:15648244-Microspheres,
pubmed-meshheading:15648244-Protein Binding,
pubmed-meshheading:15648244-Recombinant Proteins
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|
pubmed:year |
2004
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|
pubmed:articleTitle |
Adsorption of a novel recombinant glycoprotein from HIV (Env gp120dV2 SF162) to anionic PLG microparticles retains the structural integrity of the protein, whereas encapsulation in PLG microparticles does not.
|
|
pubmed:affiliation |
Chiron Vaccines, Chiron Corporation, Emeryville, California 94608, USA. manmohan_singh@chiron.com
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pubmed:publicationType |
Journal Article,
Comparative Study
|
