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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-12
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pubmed:abstractText |
Children exposed during pregnancy to the anticonvulsant drugs phenytoin, phenobarbital, and carbamazepine as monotherapy and polytherapy have an increased frequency of midface and digit hypoplasia. Some children also have cognitive dysfunction. The hypothesis tested is that the anticonvulsant drug-exposed child with midface and digit hypoplasia is more likely to have cognitive dysfunction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-3476
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
118-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:15644835-Abnormalities, Drug-Induced,
pubmed-meshheading:15644835-Anticonvulsants,
pubmed-meshheading:15644835-Carbamazepine,
pubmed-meshheading:15644835-Child,
pubmed-meshheading:15644835-Cognition Disorders,
pubmed-meshheading:15644835-Face,
pubmed-meshheading:15644835-Facies,
pubmed-meshheading:15644835-Female,
pubmed-meshheading:15644835-Fingers,
pubmed-meshheading:15644835-Follow-Up Studies,
pubmed-meshheading:15644835-Humans,
pubmed-meshheading:15644835-Intelligence Tests,
pubmed-meshheading:15644835-Phenobarbital,
pubmed-meshheading:15644835-Phenytoin,
pubmed-meshheading:15644835-Pregnancy,
pubmed-meshheading:15644835-Prenatal Exposure Delayed Effects,
pubmed-meshheading:15644835-Risk Factors,
pubmed-meshheading:15644835-Toes
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pubmed:year |
2005
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pubmed:articleTitle |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
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pubmed:affiliation |
Genetics and Teratology Unit, Massachusetts General Hospital, Boston, MA 02115, USA. holmes.lewis@mgh.harvard.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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