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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-1-11
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pubmed:abstractText |
Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disease characterized by platelet destruction. Glucocorticoids are the first-choice treatment, resulting in a complete (CR) or partial (PR) response in 70-80% of cases. In most cases, however, response is transient or glucocorticoid-dependent. For these and for selected patients with acute refractory ITP, splenectomy may produce a good response (CR+PR) in about 60-80% of cases. We report here the long-term outcome of a large cohort of ITP splenectomized patients.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1592-8721
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
90
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
72-7
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pubmed:meshHeading |
pubmed-meshheading:15642672-Adolescent,
pubmed-meshheading:15642672-Adult,
pubmed-meshheading:15642672-Aged,
pubmed-meshheading:15642672-Aged, 80 and over,
pubmed-meshheading:15642672-Analysis of Variance,
pubmed-meshheading:15642672-Child,
pubmed-meshheading:15642672-Child, Preschool,
pubmed-meshheading:15642672-Disease-Free Survival,
pubmed-meshheading:15642672-Female,
pubmed-meshheading:15642672-Humans,
pubmed-meshheading:15642672-Infant,
pubmed-meshheading:15642672-Male,
pubmed-meshheading:15642672-Middle Aged,
pubmed-meshheading:15642672-Platelet Count,
pubmed-meshheading:15642672-Postoperative Complications,
pubmed-meshheading:15642672-Prognosis,
pubmed-meshheading:15642672-Purpura, Thrombocytopenic, Idiopathic,
pubmed-meshheading:15642672-Remission Induction,
pubmed-meshheading:15642672-Retrospective Studies,
pubmed-meshheading:15642672-Splenectomy,
pubmed-meshheading:15642672-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Efficacy and safety of splenectomy in immune thrombocytopenic purpura: long-term results of 402 cases.
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pubmed:affiliation |
Hematology and Oncology Institute L. and A. Seràgnoli, University of Bologna. nvianel@med.unibo.it
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pubmed:publicationType |
Journal Article,
Multicenter Study
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